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Advancing drug discovery with innovative biophysical characterization

Malvern Panalytical collaborates with Domainex, a leading Contract Research Organization (CRO), to advance drug discovery with cutting-edge biophysics technology. Domainex uses Malvern Panalytical’s WAVEsystem and PEAQ-ITC instruments to measure drug-target binding kinetics, binding affinity, and thermodynamics in real-time. Powered by Grating-Coupled Interferometry (GCI) technology, the WAVEsystem offers exceptional sensitivity for fragment screening and faster dissociation rates, providing efficient, high-quality results. The PEAQ-ITC Isothermal Titration Calorimeter provides gold-standard data using binding heat measurements to deliver key insights into binding affinity, thermodynamics, and stoichiometry. Malvern Panalytical partners in discovery with Domainex, our advanced analytical solutions enhancing the CRO’s ability to provide fast, top-quality data, driving innovation in the life sciences and accelerating drug discovery – all helping to make the world cleaner, healthier and more productive.
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Omega/Theta Demo at your desk

Determining crystal orientation is crucial in semiconductor production. The Omega/Theta is the solution to accomplish this step quickly and accurately . This X-ray diffractometer comes with fully automated vertical three-axes and features such as mapping and stacking stages, rocking curve capabilities and many more. By combining the Azimuthal scan method with flexible sample handling, the Omega/Theta XRD can provide full measurements for all single crystalline materials in as few as 10 seconds. In this Demo, we reveal the measurement procedures for different types of samples such as irregular single crystalline samples and wafer samples. The procedure is done with the help of the XRD Suite, both a powerful and intuitive software, making it convenient and easy to operate for a range of users.
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From Eruption to Insight: The Science Behind Volcanic Ash Analysis

A volcanic eruption is a powerful natural event that can lead to extensive disruption and damage. Explosive eruptions produce micron sized fragments of volcanic rock termed “ash” which get released high into the atmosphere and can have far-reaching impacts on both local communities and global networks. To minimize the risks of volcanic eruptions, computer models are now used to anticipate the movement of volcanic ash. Accurate, detailed information about particle size and shape means volcanologists can accurately predict how fast and how far away volcanic ash will fall. Malvern Panalytical’s Mastersizer 3000+ and Hydro Insight are a powerful combination used to measure particle size and shape. For researchers, our goal is to supply the tools that will help them to predict where volcanic ash will travel during eruptions, to help them mitigate the risks to humans and infrastructure.
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SDCOM Demo at your desk

Your ultra-fast, top surface measuring crystal orientation in a compact package, able to measure any single crystal with a diameter between 2mm to 300mm. SDCOM uses the azimuthal scan method to precisely determine the complete lattice orientation of single crystals in just one measuring rotation – taking only a few seconds. Suitable for both research, production and quality control, the versatile and accessible SDCOM fits easily into a wide range of wafer and ingot process steps while having minimal operational costs due to no requirement for water cooling. SDCOM is capable of measuring the crystal orientation of any single crystalline material. In this Demo, we reveal the measurement procedures for different types of samples such as irregular single crystalline samples, wafer samples and small samples. The procedure is done with the help of the XRD Suite, both a powerful and intuitive software, making it convenient and easy to operate for a range of users.
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From Challenge to Accuracy: Transforming Ferro-Alloy Analysis with XRF Innovative Solutions

X-ray fluorescence (XRF) has long been the preferred method for quantitative analysis in steel production due to its accuracy and reliability. But when it comes to challenging materials like Direct Reduced Iron and ferroalloys such as Ferrosilicon, Ferrochromium, and Ferromanganese, the analysis can be more complex. In this video, our expert explain how Malvern Panalytical overcomes these challenges using innovative approaches and deep expertise. From meticulous sample preparation to setting up customized applications, our team ensures the highest level of accuracy—a crucial factor in determining the value of these materials, as even small measurement errors can lead to significant price differences. Key Highlights: The importance of XRF in steel and ferroalloy production Custom calibration standards for accurate analysis Detailed fusion programs and sample preparation techniques Real-world examples of customer success in ferroalloy projects
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Using XRF on dried blood spot samples to analyze toxic metal exposure

A new study is using XRF to measure the heavy metals in our bodies in innovative & minimally invasive ways. Aaron Specht, assistant professor at Purdue University, is using X-ray fluorescence (XRF) spectrometers, including Malvern Panalytical’s Epsilon 4 system, to detect toxic metals in dried blood samples collected on filter paper without destroying them. Specht is currently leading a study that aims to shine new light on the relationship between Alzheimer’s disease and related dementias (AD/ADRD) and four toxic elements in particular: lead, mercury, arsenic and cadmium. This research has wide-ranging potential for the future monitoring of toxic metal exposure, ultimately helping make our world cleaner, healthier and more productive. Find out more about the study: https://bit.ly/3XCktPK Discover our Epsilon 4 product range: https://www.malvernpanalytical.com/en/products/product-range/epsilon-range/epsilon-4
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Revolutionising Energy Storage & Conversion: Collaboration with the University of Pittsburgh

Join us as we delve into the groundbreaking collaboration between the University of Pittsburgh’s Kumta Lab and Malvern Panalytical, aimed at transforming the landscape of energy storage and conversion. Dr. Prashant N. Kumta and his team are utilizing innovative solutions, including insights from Malvern Panalytical’s Empyrean X-ray diffractometer, to bring about significant improvements in battery technology and clean energy conversion. Follow our journey and stay updated on the latest developments in energy innovation. Don’t miss out on the chance to be part of a sustainable energy revolution! https://bit.ly/3Steo5a
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Modeling invisible plastics

You probably know what nano and microplastics are. Yes, very very small pieces of plastic. They are thought to originate from a variety of human activities, like cosmetics, clothing, industrial processes, and recycling. They are finding their way into all places on the planet, our land, seas and in living creatures, such as fish. Recently, they have also been found in human placentas. Florine Aalders at Malvern Panalytical characterised and classified the nano and microplastics that float around our planet to help a team of leading scientists in the Momentum consortium answer to important questions. Above all, how are these nano- and microplastics affecting our human species? You can also find out more about Momentum here https://momentummicroplastics.nl/ We are proud to be making a small but critical contribution by making the invisible visible we trust the project will have a positive impact on human health.
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Malvern Panalytical Pharmaceuticals

Safe, effective medicines are changing our world for the better. We work closely with our customers, applying our analytical technologies and contract drug discovery, development and manufacturing services to help you make pharmaceutical products efficiently and cost-effectively. Access the right data at the right time to accelerate drug development and ensure safe, reliable manufacture. Our partnership approach helps you find the best development routes and physicochemical analysis methods, based on your specific needs. Need an extension to your in-house team? From instrument support to development project consultancy, we’re here to help you manage your workload and budget.
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Malvern Panalytical – Analysis of paints and coatings

From pigments and particles to dispersants and binders Malvern Panalytical analysis solutions help you to determine a range of critical parameters, so that you can develop and optimize your coatings. Whether you need to monitor particle size, product chemistry or formulation stability, our analysis systems can help you make your product more economic, reliable, and sustainable. Our solutions provide insight into your nano-world, so that you can manufacture better paints and coatings. Find out more at: https://www.malvernpanalytical.com/en/industries/specialty-chemicals
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